Detailed information for KIF11
Basic information
| Official symbol | KIF11 |
|---|---|
| Official full name | kinesin family member 11 |
| Location | 10q24.1 |
| Gene type | protein-coding |
| Synonyms | EG5|HKSP|KNSL1|MCLMR|TRIP5 |
| Quick links | Entrez ID:3832; HGNC:6388; MIM:148760; Ensembl:ENSG00000138160; HPRD:01023; Vega:OTTHUMG00000018761 |
GO related
| GO term accession | GO term name | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-Value |
|---|---|---|---|---|---|---|---|
| GO:0044707 | single-multicellular organism process | 5612 | 143 | 69.81 | 2.05 | 9.21e-29 | 7.72e-27 |
| GO:0032501 | multicellular organismal process | 5644 | 143 | 70.21 | 2.04 | 1.83e-28 | 1.43e-26 |
| GO:0044699 | single-organism process | 7682 | 152 | 95.57 | 1.59 | 9.26e-19 | 3.88e-17 |
| GO:0048856 | anatomical structure development | 4030 | 102 | 50.13 | 2.03 | 4.19e-16 | 1.33e-14 |
| GO:0032502 | developmental process | 4572 | 104 | 56.88 | 1.83 | 3.53e-13 | 1.04e-11 |
| GO:0005488 | binding | 11955 | 150 | 132.97 | 1.13 | 0.0005 | 0.0090 |
| GO:0005515 | protein binding | 7337 | 102 | 81.61 | 1.25 | 0.0011 | 0.0149 |
| GO:0043168 | anion binding | 2402 | 40 | 26.72 | 1.50 | 0.0048 | 0.0336 |
| GO:0015630 | microtubule cytoskeleton | 863 | 37 | 9.41 | 3.93 | 5.76e-13 | 8.68e-12 |
| GO:0044430 | cytoskeletal part | 1287 | 39 | 14.04 | 2.78 | 3.99e-09 | 3.91e-08 |
| GO:0005856 | cytoskeleton | 1790 | 47 | 19.52 | 2.41 | 7.23e-09 | 6.16e-08 |
Pathway related
| Term | Surce | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|
PPI related
| ID | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|
OMIM related
| chromosome | begin | end | disorder MIM number | disorder | phene mapping key | gene/locus MIM number | cytogenetic loaction |
|---|---|---|---|---|---|---|---|
| chr10 | 94351824 | 94416152 | 152950 | "Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation" | 3 | 148760 | 10q23.33 |
MGI related
| chromosome | begin | end | gene ID | gene symbol of mouse | MGI | MP | phenotype description |
|---|---|---|---|---|---|---|---|
| chr10 | 94351824 | 94416152 | 3832 | Kif11 | MGI:1098231 | MP:0005378 | growth/size phenotype |
| chr10 | 94351824 | 94416152 | 3832 | Kif11 | MGI:1098231 | MP:0005380 | embryogenesis phenotype |
| chr10 | 94351824 | 94416152 | 3832 | Kif11 | MGI:1098231 | MP:0005389 | reproductive system phenotype |
| chr10 | 94351824 | 94416152 | 3832 | Kif11 | MGI:1098231 | MP:0010768 | mortality/aging |
Mutation spectrum
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Gene-disease network
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