Detailed information for PRPF3
Basic information
| Official symbol | PRPF3 |
|---|---|
| Official full name | pre-mRNA processing factor 3 |
| Location | 1q21.1 |
| Gene type | protein-coding |
| Synonyms | HPRP3|HPRP3P|PRP3|Prp3p|RP18|SNRNP90 |
| Quick links | Entrez ID:9129; HGNC:17348; MIM:607301; Ensembl:ENSG00000117360; HPRD:07389; Vega:OTTHUMG00000012807 |
GO related
| GO term accession | GO term name | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-Value |
|---|---|---|---|---|---|---|---|
| GO:0005488 | binding | 11955 | 150 | 132.97 | 1.13 | 0.0005 | 0.0090 |
| GO:0005515 | protein binding | 7337 | 102 | 81.61 | 1.25 | 0.0011 | 0.0149 |
Pathway related
| Term | Surce | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|---|---|---|---|---|---|---|
| Spliceosome | KEGG | 127 | 6 | 0.57 | 10.50 | 2.52e-05 | 0.0002 |
| mRNA processing | WIKI | 132 | 4 | 0.59 | 6.74 | 0.0031 | 0.0114 |
PPI related
| ID | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|
OMIM related
| chromosome | begin | end | disorder MIM number | disorder | phene mapping key | gene/locus MIM number | cytogenetic loaction |
|---|
MGI related
| chromosome | begin | end | gene ID | gene symbol of mouse | MGI | MP | phenotype description |
|---|---|---|---|---|---|---|---|
| chr1 | 150292927 | 150326704 | 9129 | Prpf3 | MGI:1918017 | MP:0001186 | pigmentation phenotype |
| chr1 | 150292927 | 150326704 | 9129 | Prpf3 | MGI:1918017 | MP:0005391 | vision/eye phenotype |
| chr1 | 150292927 | 150326704 | 9129 | Prpf3 | MGI:1918017 | MP:0010768 | mortality/aging |
Mutation spectrum
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Gene-disease network
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