Detailed information for PRPF6
Basic information
| Official symbol | PRPF6 |
|---|---|
| Official full name | pre-mRNA processing factor 6 |
| Location | 20q13.33 |
| Gene type | protein-coding |
| Synonyms | ANT-1|ANT1|C20orf14|Prp6|SNRNP102|TOM|U5-102K|hPrp6 |
| Quick links | Entrez ID:24148; HGNC:15860; MIM:613979; Ensembl:ENSG00000101161; HPRD:10729; Vega:OTTHUMG00000033018 |
GO related
| GO term accession | GO term name | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-Value |
|---|---|---|---|---|---|---|---|
| GO:0005488 | binding | 11955 | 150 | 132.97 | 1.13 | 0.0005 | 0.0090 |
| GO:0005515 | protein binding | 7337 | 102 | 81.61 | 1.25 | 0.0011 | 0.0149 |
| GO:0030532 | small nuclear ribonucleoprotein complex | 33 | 5 | 0.36 | 13.89 | 2.71e-05 | 0.0002 |
| GO:0046540 | U4/U6 x U5 tri-snRNP complex | 4 | 2 | 0.04 | 45.84 | 0.0007 | 0.0034 |
Pathway related
| Term | Surce | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|---|---|---|---|---|---|---|
| Spliceosome | KEGG | 127 | 6 | 0.57 | 10.50 | 2.52e-05 | 0.0002 |
PPI related
| ID | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|---|---|---|---|---|---|
| Hsapiens_Module_918 | 87 | 6 | 0.89 | 6.72 | 0.0003 | 0.0022 |
| Hsapiens_Module_691 | 121 | 6 | 1.24 | 4.83 | 0.0016 | 0.0092 |
OMIM related
| chromosome | begin | end | disorder MIM number | disorder | phene mapping key | gene/locus MIM number | cytogenetic loaction |
|---|---|---|---|---|---|---|---|
| chr20 | 62611430 | 62665453 | 613983 | Retinitis pigmentosa 60 | 3 | 613979 | 20q13.33 |
MGI related
| chromosome | begin | end | gene ID | gene symbol of mouse | MGI | MP | phenotype description |
|---|---|---|---|---|---|---|---|
| chr20 | 62611430 | 62665453 | 24148 | Prpf6 | MGI:1922946 | - | - |
Mutation spectrum
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Gene-disease network
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