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    Top 5 diseases

    Data summary

    • Publications : 991
    • Phenotypes : 178
    • Genes : 207
    • Mutations : 4571
    • SNVs : 3402
    • InDels : 1169
    • Last Update : 26/10/2017

    Detailed information for SEMA4A






    Basic information
    Official symbolSEMA4A
    Official full namesema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
    Location1q22
    Gene typeprotein-coding
    SynonymsCORD10|RP35|SEMAB|SEMB
    Quick linksEntrez ID:64218; HGNC:10729; MIM:607292; Ensembl:ENSG00000196189; HPRD:09528; Vega:OTTHUMG00000014042
    GO related
    GO term accessionGO term nameNumber of reference genesNumber of genesExpected numberRatio of enrichmentP-valueAdjusted P-Value
    GO:0044707single-multicellular organism process561214369.812.059.21e-297.72e-27
    GO:0032501multicellular organismal process564414370.212.041.83e-281.43e-26
    GO:0044699single-organism process768215295.571.599.26e-193.88e-17
    GO:0048646anatomical structure formation involved in morphogenesis15946219.833.134.32e-171.64e-15
    GO:0009653anatomical structure morphogenesis20557025.562.741.99e-167.08e-15
    GO:0030030cell projection organization9344611.623.962.85e-169.84e-15
    GO:0048856anatomical structure development403010250.132.034.19e-161.33e-14
    GO:0000902cell morphogenesis9454211.763.572.49e-137.69e-12
    GO:0032502developmental process457210456.881.833.53e-131.04e-11
    Pathway related
    TermSurceNumber of reference genesNumber of genesExpected numberRatio of enrichmentP-valueAdjusted P-value
    PPI related
    IDNumber of reference genesNumber of genesExpected numberRatio of enrichmentP-valueAdjusted P-value
    OMIM related
    chromosomebeginenddisorder MIM numberdisorderphene mapping keygene/locus MIM numbercytogenetic loaction
    chr1156122321156148542610283Cone-rod dystrophy 1036072921q22
    chr1156122321156148542610282Retinitis pigmentosa 3536072921q22
    MGI related
    chromosomebeginendgene IDgene symbol of mouseMGIMPphenotype description
    chr115612232115614854264218Sema4aMGI:107560MP:0001186pigmentation phenotype
    chr115612232115614854264218Sema4aMGI:107560MP:0003631nervous system phenotype
    chr115612232115614854264218Sema4aMGI:107560MP:0005384cellular phenotype
    chr115612232115614854264218Sema4aMGI:107560MP:0005387immune system phenotype
    chr115612232115614854264218Sema4aMGI:107560MP:0005391vision/eye phenotype
    chr115612232115614854264218Sema4aMGI:107560MP:0005397hematopoietic system phenotype
    Mutation spectrum

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    Gene-disease network

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